hrp0095fc5.6 | Adrenals and HPA Axis | ESPE2022

ACTH Stimulation Decreases Ischemia-Modified Albumin Levels In Vivo

Muratoglu Sahin Nursel , Esen Senem , Savas Erdeve Senay , Budak Fatma , Neselioglu Salim , Erel Ozcan , Cetinkaya Semra

Introduction: The production of ischemia-modified albumin (IMA) is associated with the production of reactive oxygen species modifying the metal-binding sites of albumin. IMA is considered a non-specific early biomarker in the evaluation of oxidative stress status. Cortisol is known to trigger anti-inflammatory actions through genomic and non-genomic pathways that eventually lead to decreased production of cytokines, chemokines, and inducible nitric oxide synt...